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Publications
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* co-first authors
41. "Programming Aptamer-Protein Complexation Kinetics via Modulation of G-quadruplex Secondary Structure"
Journal of the American Chemical Society (2025)
C. D Flynn*, D. Chang*, Y. Lee, S. Isaacson, Z. Wu, J. Rivnay, S. O Kelley
40. "Dual-Chronoamperometry Drift Correction for Electrochemical Sensors"
ACS Sensors (2025)
K. T Riordan, K. Yang, E. Brazelton, M. A Eslami, A. Copenhaver, F. Esmaeili, C. D. Flynn, Z. Wu, S. Isaacson, D. Chang, M. D Cabezas, V. Juska, J. Das, E. H Sargent, S. O Kelley
39. "Nanobody Receptors Enable High-Sensitivity Monitoring of IL-6 Using Molecular Pendulum Bioanalysis"
Analytical Chemistry (2025)
C. D Flynn, Z. Wu, A. Bantle, S. E Isaacson, D. Chang, A. Mahmud, H. Yousefi, J. Das, S. O Kelley
38. "Active-reset protein sensors enable continuous in vivo monitoring of inflammation"
Science (2024)
H Zargartalebi, S Mirzaie, A GhavamiNejad, S. Ahmed, F Esmaeili, A Geraili, C. Flynn, D. Chang, J. Das, A Abdrabou, E. H Sargent, S. O Kelley
37. "Artificial intelligence in point-of-care biosensing: challenges and opportunities"
Diagnostics (2024)
C. D Flynn*, D. Chang*
36. "Highly Stable Biotemplated InP/ZnSe/ZnS Quantum Dots for In Situ Bacterial Monitoring"
ACS Applied Materials & Interfaces (2024)
H. Yousefi, L. K. Sagar, A. Geraili, D. Chang, F P. García de Arquer, C. D Flynn, S. Lee, E. H Sargent, S. O Kelley
35. "Self-assembled monolayer transporters enable reagentless analysis of small molecule analytes"
ACS Sensors (2024)
C. D Flynn, K. T Riordan, T. L Young, D. Chang, Z. Wu, S. E Isaacson, H. Yousefi, J. Das, S. O Kelley
34. "A high-dimensional microfluidic approach for selection of aptamers with programmable binding affinities"
Nature Chemistry (2023)
D. Chang*, Z. Wang*, C. D Flynn, A. Mahmud, M. Labib, H. Wang, A. Geraili, X. Li, J. Zhang, E. H Sargent, S. O Kelley
33. "A Colorimetric Biosensing Platform with Aptamers, Rolling Circle Amplification and Urease‐Mediated Litmus Test"
Angewandte Chemie International Edition (2023)
D. Chang*, J. Li*, R. Liu*, M. Liu, K. Tram, N. Schmitt, Y. Li
32. "Apta FastZ: An Algorithm for the Rapid Identification of Aptamers with Defined Binding Affinities"
Analytical Chemistry (2023)
Z. Wang*, D. Chang*, E. H Sargent, S. O Kelley,
31. "Biomolecular sensors for advanced physiological monitoring"
Nature Reviews Bioengineering (2023)
C. D Flynn, D. Chang, A. Mahmud, H. Yousefi, J. Das, K. T Riordan, E. H Sargent, S. O Kelley
30. "Nucleic acid enzyme‐activated CRISPR‐cas12a with circular CRISPR RNA for biosensing"
Small (2023)
Y. Wu, D. Chang, Y. Chang, Q. Zhang, Y. Liu, J. D Brennan, Y. Li, M. Liu, J. D Brennan, Y. Li
29. "In vitro selection and characterization of a DNAzyme probe for diverse pathogenic strains of Clostridium difficile"
Chemistry–A European Journal (2023)
S. Qian, D. Chang, J. Gu, B. J Salena, Y. Li
28. "Monitoring Cardiac Biomarkers with Aptamer‐Based Molecular Pendulum Sensors"
Angewandte Chemie International Edition (2023)
A. Mahmud, D. Chang, J. Das, S. Gomis, F. Foroutan, J. B Chen, L. Pandey, C. D Flynn, H. Yousefi, A. Geraili, H. J Ross, E. H Sargent, S. O Kelley
27. "Engineering a ligase binding DNA aptamer into a templating DNA scaffold to guide the selective synthesis of circular DNAzymes and DNA aptamers"
Journal Of The American Chemical Society (2023)
Y. Yan, D. Chang, Y. Xu, Y. Chang, Q. Zhang, Q. Yuan, B. J Salena, Y. Li, M. Liu
26. "An RNA‐Cleaving DNAzyme That Requires an Organic Solvent to Function"
Angewandte Chemie International Edition (2023)
T. Chang, G. Li, D. Chang, R. Amini, X. Zhu, T. Zhao, J. Gu, Z. Li, Y. Li
25. "Aptamers from random sequence space: Accomplishments, gaps and future considerations"
Analytica Chimica Acta (2022)
S. Qian, D. Chang, S. He, Y. Li
24. "A DNA barcode‐based aptasensor enables rapid testing of porcine epidemic diarrhea viruses in swine saliva using electrochemical readout"
Angewandte Chemie International Edition (2022)
A. Victorious, Z. Zhang, D. Chang, R. Maclachlan, R. Pandey, J. Xia, J. Gu, T. Hoare, L. Soleymani, Y. Li
23. "Functional nucleic acids for pathogenic bacteria detection"
Accounts Of Chemical Research (2021)
D. Chang*, S. Zakaria*, S. Esmaeili Samani, Y. Chang, C. D. Filipe, L. Soleymani, J. D Brennan, M. Liu, Y. Li
22. "A Highly Specific DNA Aptamer for RNase H2 from Clostridium difficile"
ACS Applied Materials & Interfaces (2021)
J. Li, J. Gu, H. Zhang, R. Liu, W. Zhang, M. Mohammed-Elsabagh, J. Xia, D. Morrison, S. Zakaria, D. Chang, A. Arrabi, Y. Li
21. "A DNA nanoflower‐assisted separation‐free nucleic acid detection platform with a commercial pregnancy test strip"
Angewandte Chemie International Edition (2021)
L. Qi, M. Yang, D. Chang, W. Zhao, S. Zhang, Y. Du, Y. Li
20. "Rapid and specific imaging of extracellular signaling molecule adenosine triphosphate with a self-phosphorylating DNAzyme"
Journal Of The American Chemical Society (2021)
D. Zhao, D. Chang, Q. Zhang, Y. Chang, B. Liu, C. Sun, Z. Li, C. Dong, M. Liu, Y. Li
19. "Integrating programmable DNAzymes with electrical readout for rapid and culture-free bacterial detection using a handheld platform"
Nature Chemistry (2021)
R. Pandey, D. Chang, M. Smieja, T. Hoare, Y. Li, L. Soleymani
18. "A Syringe‐Based DNAzyme Sensor for Bacterial Detection"
Analysis & Sensing (2021)
S. Esmaeili Samani, E. McConnell, D. Chang, M. Rothenbroker, C. Filipe, Y. Li
17. "Detection of SARS-CoV-2 Viral Particles using Direct, Reagent-Free Electrochemical Sensing"
Journal of the American Chemical Society (2021)
H. Yousefi*, A. Mahmud*, D. Chang*, J. Das, S. Gomis, J. B Chen, H. Wang, T. Been, L. Yip, E. Coomes, Z. Li, S. Mubareka, A. McGeer, N. Christie, S. Gray-Owen, A. Cochrane, J. M. Rini, E. H Sargent, S. O Kelley
16. "An unintentional discovery of a fluorogenic DNA probe for ribonuclease I"
Chembiochem (2020)
D. Chang, T. Chang, B. Salena, Y. Li
15. "Ribbon of DNA lattice on gold nanoparticles for selective drug delivery to cancer cells"
Angewandte Chemie International Edition (2020)
S. Zhang, C. Chen, C. Xue, D. Chang, H. Xu, B. J Salena, Y. Li, Z. Wu
14. "Evolution of a highly functional circular DNA aptamer in serum"
Nucleic Acids Research (2020)
M. Liu, W. Zhang, D. Chang, Q. Zhang, J. D Brennan, Y. Li, L. Zheng
13. "In vitro selection of a DNA aptamer targeting degraded protein fragments for biosensing"
Angewandte Chemie International Edition (2020)
M. Liu, J. Wang, Y. Chang, Q. Zhang, D. Chang, C. Y Hui, J. D Brennan, Y. Li
12. "Highly Sensitive RNA‐Cleaving DNAzyme Sensors from Surface‐to‐Surface Product Enrichment"
Chembiochem (2019)
S. E. Samani*, D. Chang*, E. M McConnell, M. Rothenbroker, C. D. Filipe, Y. Li
11. "Target‐induced catalytic assembly of Y‐shaped DNA and its application for in situ imaging of microRNAs"
Angewandte Chemie International Edition (2018)
C. Xue, S. Zhang, C. Ouyang, D. Chang, B. J Salena, Y. Li, Z. Wu
10. "In vitro selection of DNA aptamers that bind geniposide"
Molecules (2017)
A. Zhang, D. Chang, Z. Zhang, F. Li, W. Li, X. Wang, Y. Li, Q. Hua
9. "Optical biosensors utilizing graphene and functional DNA molecules"
Journal Of Materials Research (2017)
S. Manochehry, M. Liu, D. Chang, Y. Li
8. "Discovery and biosensing applications of diverse RNA-cleaving DNAzymes"Accounts Of Chemical Research (2017)
M. Liu, D. Chang, Y. Li
7. "Detection of DNA amplicons of polymerase chain reaction using litmus test"
Scientific Reports (2017)
D. Chang, K. Tram, B. Li, Q. Feng, Z. Shen, C. H Lee, B. J Salena, Y. Li
6. "A DNAzyme feedback amplification strategy for biosensing"
Angewandte Chemie International Edition (2017)
M. Liu, W. Zhang, D. Chang, Q. Zhang, J. D Brennan, Y. Li
5. "In vitro selection of RNA-cleaving DNAzymes for bacterial detection"
Methods (2016)
W. Zhang, Q. Feng, D. Chang, K. Tram, Y. Li
4. "Colorimetric detection of bacteria using litmus test"
Journal Of Visualized Experiments: Jove (2016)
K. Tram, S. Manochehry, Q. Feng, D. Chang, B. J Salena, Y. Li
3. "Integrating deoxyribozymes into colorimetric sensing platforms"
Sensors (2016)
D. Chang, S. Zakaria, M. Deng, N. Allen, K. Tram, Y. Li
2. "A catalytic DNA activated by a specific strain of bacterial pathogen"
Angewandte Chemie International Edition (2015)
Z. Shen*, Z. Wu*, D. Chang*, W. Zhang, K. Tram, C. Lee, P. Kim, B. J Salena, Y. Li
1. "Integrating graphene oxide, functional DNA and nucleic-acid-manipulating strategies for amplified biosensing"
Trends in Analytical Chemistry (2015)
M. Liu, W. Zhang, D. Chang, Q. Zhang, J. D Brennan, Y. Li
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